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Independent pharmacies in Columbus, MS

5 independent, locally-owned pharmacies are listed in Columbus, Mississippi on CheckThisBiz. National chains and franchises are not included. Ranked by how much we could independently verify (listing sources, phone, website and owner verification), the top pharmacies are Chris' Pharmacy And Sons Too, Southern Drugs and Chris' Pharmacy.

How we rank: email-verified customer reviews on CheckThisBiz first, then independent checks (listing sources, phone, website and domain, owner verification). Paid placement never changes this ranking. Our methods · Sources · Updated November 14, 2026

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5 pharmacies in Columbus · Clear

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Chris' Pharmacy And Sons Too

Pharmacy

115 Alabama St, Columbus, MS

Strong signals

Southern Drugs

Pharmacy

1202 Main St, Columbus, MS

Strong signals

Chris' Pharmacy

Pharmacy

2320 5th St N, Columbus, MS

Good signals

Robert's Apothecary

Pharmacy

2219 5th St N, Columbus, MS

Good signals

Family Pharmacy at Leigh Mall Shell

Pharmacy

1214 Highway 45 N, Columbus, MS

Good signals

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