Three Sisters Pie Co.
Cafe422 Main St, Columbus, MS
Food & Drink
Independent cafes in Columbus, MS
5 independent, locally-owned cafes are listed in Columbus, Mississippi on CheckThisBiz. National chains and franchises are not included. Ranked by how much we could independently verify (listing sources, phone, website and owner verification), the top cafes are Three Sisters Pie Co., Cafe On Main and Homepro HC24/7-Gia Dụng Thông Minh.
How we rank: email-verified customer reviews on CheckThisBiz first, then independent checks (listing sources, phone, website and domain, owner verification). Paid placement never changes this ranking. Our methods · Sources · Updated November 15, 2026
View on map5 cafes in Columbus · Clear
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Cafe On Main
Cafe101 5th St S, Columbus, MS
Homepro HC24/7-Gia Dụng Thông Minh
Cafe58 Center Rd, Columbus, MS
Vibe Café
Cafe500 Holly Hills Rd, Columbus, MS
Some signals
1514 Caffeine
Cafe1514 Main St, Columbus, MS
Some signals
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